Aguero missed City's 3-1 victory over Bournemouth on Saturday with a muscle strain, the Argentina forward watching from the stands as Guardiola's team moved five points clear at the top of the table. "Today we had a reason for the fragility".
Cedric Soares lined up the resulting free-kick 20 yards from goal and curled a superb effort over the United wall and into the top corner of De Gea's net.
That sparked what is fast becoming a trademark recovery from United. More impressive work from Rashford led to the second goal, the striker crossing for Ander Herrera to flick in deftly at the near post.
Should Diaz leave, it will be the second time in recent seasons one of City's brightest prospects has chose to leave the Etihad, after Jadon Sancho joined Borussia Dortmund last summer in search of regular first-team football.
This time previous year, Pep Guardiola left City's record goalscorer on the bench for the Manchester derby at Old Trafford.
Manchester City were always unlikely to risk Sergio Aguero for the trip to Watford and it was no surprise he wasn't spotted among Pep Guardiola's charges boarding the train on Tuesday.
2:05 Highlights from Bournemouth's win over Huddersfield in the Premier League
Sane helped City fight past Bournemouth on Saturday after Cherries striker Callum Wilson struck before half-time to ensure the sides were level at the interval, after Bernardo Silva had put the hosts into the lead.
Premier League football is back for a bumper midweek round of games.
Watford's miserable afternoon was compounded in the closing stages when Etienne Capoue was given a straight red card after an apparent two-footed challenge on Kelechi Iheanacho. That it is the challengers who make the champion better.
Six minutes later, it was 2-2 when Rashford got to the byline and cut the ball into the six-yard box, where Herrera nipped in front of his marker to score with a cute back-heel that McCarthy got a hand to but could not keep out.
"I think it is too early to see how decisive it is", Guardiola said of City's advantage. "I needed to make an impact".
Javi Gracia's team were confident enough to give City a game rather than spend 90 minutes sitting deep on a damage limitation exercise, but ultimately, it wasn't enough against the leaders.
Mathias Jorgensen opened the scoring for Huddersfield in the first minute, but they suffered a 2-1 defeat against Brighton, who came from behind to win for the first time in the Premier League.
Turkish President Recep Tayyip Erdogan, who has been sharply critical of Saudi Arabia over the incident, is also in attendance. The two sides also held discussions on enhancing investment in technology, renewable energy and food security .
However, with around 90 Conservative MPs pledged to vote down the deal, the prime minister faces a major struggle to win the vote. Asked if she could survive a defeat on her Withdrawal Agreement, he added: "Each of us has to make that decision on December 11".
The alleged Google Pixel Lite is stacked against Google Pixel, Pixel 3 XL , iPhone XS, iPhone X, iPhone XR . From the image also, it looks like the Pixel 3 Lite might not have stereo front speakers like the Pixel 3 .
The debate is being carried out as a caravan of Central American migrants at the US-Mexico border has been making headlines. And the journey, which began for majority in Honduras, Guatemala and El Salvador, is also taking a physical toll.
While Priyanka was in the capital shooting for her film until a few days back, fiancé Nick Jonas landed in India last week. As per reports that are doing the rounds, Shruti's wedding will be a two-day affair with sangeet and mehendi functions.
But Everton could also point to two glorious first-half chances that might have ended their 19-year wait for a win at Anfield . I can not tell you if it was disrespectful because I didn't see it. "It's nothing too serious we don't think", said Dyche.
With the help of dozens of passers-by they managed to get the grate off and search underneath for at least two hours. The couple reportedly went to the police for help, but officials were unable to locate the ring and the couple left.
The suite of geophysical instruments on InSight sounds like a doctor's bag, giving Mars its first "checkup" since it formed. The odds are in NASA's favor, but it will be some time until the world finds out whether the landing is successful.
Petersburg's economic forum", Peskov, who was with Putin at an global summit in Argentina, said Saturday. Cohen previous year acknowledged to Congress that he sent the emails to Peskov in January 2016.
Trump, who has expressed anger over GM's closing of American auto plants this week, retweeted the tweet without comment. GM said it has invested more than $22 billion in US operations since 2009, when it exited bankruptcy protection.
The Browns improved to 4-6-1 on the season and are three games back of the Pittsburgh Steelers in the AFC North. Mayfield wasn't the only Browns player to interact with Jackson on Sunday.
Kareem Hunt 'embarrassed' by video of attack on woman
Hunt is shown being restrained several times by friends before pushing a woman to the ground, when he proceeds to kick her. We won't let anything that happens on the outside dictate or control what we have inside. "It's a tough situation".
At G-20, possible 'breakthrough' seen after trade talks
The annual summit of leaders of the top 20 economies of the world is being attended by Prime Minister Narendra Modi. Trump was also scheduled to speak with German Chancellor Angela Merkel and Turkish President Recep Tayyip Erdogan.
Fed chair says economy is in ‘good health’ despite risks
Since then, he and other Fed officials have sounded a bit more cautious, nodding to a slowdown in Europe, Japan and China. In the week ahead, the Fed will see one of the last big economic statistics before its next interest rate decision.
NBA Report: Cavs Players Upset By Kyle Korver Trade to Utah 3
He will make $7.56 million this year and has $7.5 million on his deal for next year, although less than half of it is guaranteed. In three seasons with Cleveland, he averaged 9.3 points per game, mostly scoring his points from jumpers and three-point shots.
Conservative vs. moderate in Mississippi Senate election
On Nov. 15, another video surfaced online in which Hyde-Smith said making it more hard for people to vote is a "great idea". Jones said he has been "an independent voice for the state of Alabama", and Espy would be the same for Mississippi.